Low-toxicity metallosomes for biomedical applications by self-assembly of organometallic metallosurfactants and phospholipids.

M Marín-García Nuria Benseny-Cases Mercedes Camacho Joan Suades Ramon Barnadas-Rodríguez

Published in: Chemical communications (Cambridge, England) (2018)

A new and convenient strategy for the preparation of metallosomes has been developed by mixing organometallic metallosurfactants and phospholipids. These aggregates show the characteristic properties of liposomes (stability upon dilution and low toxicity) and the toxicity is at least ten-fold lower than that of the metallosurfactant aggregates without phospholipids.

Keyphrases

oxidative stress
fatty acid
drug delivery
oxide nanoparticles
ms ms