Idiopathic pulmonary fibrosis: current diagnosis and treatment.
Alexandre Franco AmaralPhilippe de Figueiredo Braga ColaresRonaldo Adib KairallaPublished in: Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia (2023)
Idiopathic pulmonary fibrosis (IPF) is a devastating chronic lung disease without a clear recognizable cause. IPF has been at the forefront of new diagnostic algorithms and treatment developments that led to a shift in patients' care in the past decade, indeed influencing the management of fibrotic interstitial lung diseases other than IPF itself. Clinical presentation, pathophysiology, and diagnostic criteria are briefly addressed in this review article. Additionally, evidence regarding the use of antifibrotics beyond the settings of clinical trials, impact of comorbidities, and therapeutic approaches other than pharmacological treatments are discussed in further detail.
Keyphrases
- idiopathic pulmonary fibrosis
- interstitial lung disease
- clinical trial
- end stage renal disease
- ejection fraction
- newly diagnosed
- healthcare
- chronic kidney disease
- palliative care
- machine learning
- prognostic factors
- randomized controlled trial
- deep learning
- rheumatoid arthritis
- systemic sclerosis
- chronic pain
- patient reported
- affordable care act
- phase ii