Transplantation Without Overimmunosuppression (TWO) study protocol: a phase 2b randomised controlled single-centre trial of regulatory T cell therapy to facilitate immunosuppression reduction in living donor kidney transplant recipients.

Matthew Oliver BrookJoanna HesterWilliam PetcheyInes RombachSusan DuttonMatthew James BottomleyJoanna BlackSeetha Abdul-WahabAndrew BushellGiovanna LombardiKathryn WoodPeter FriendPaul HardenFadi Issa

Published in: BMJ open (2022)

ISRCTN: 11038572; Pre-results.

Keyphrases

cell therapy
study protocol
randomized controlled trial
stem cells
clinical trial
mesenchymal stem cells
open label
transcription factor
double blind
placebo controlled
phase iii
phase ii