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DNA binding to TLR9 expressed by red blood cells promotes innate immune activation and anemia.

L K Metthew LamSophia MurphyDimitra KokkinakiAlessandro VenosaScott Sherrill-MixCarla CasuStefano RivellaAaron I WeinerJeongho ParkSunny ShinAndrew E VaughanBeatrice H HahnAudrey R Odom JohnNuala J MeyerChristopher A HunterG Scott WorthenNilam S Mangalmurti
Published in: Science translational medicine (2021)
[Figure: see text].
Keyphrases
  • dna binding
  • innate immune
  • red blood cell
  • transcription factor
  • toll like receptor
  • inflammatory response
  • chronic kidney disease
  • immune response
  • iron deficiency
  • smoking cessation
  • nuclear factor