Andrew E Vaughan (A E Vaughan)

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 45

Top Topics

Acute Respiratory Distress Syndrome

Pulmonary Fibrosis

Top Venues

Nature communications

Science translational medicine

NPJ Regenerative medicine

bioRxiv : the preprint server for biology

This page only lists publications with an associated author ORCID identifier.

Publications

Xuexiang Han, Mohamad-Gabriel Alameh, Ningqiang Gong, Lulu Xue, Majed Ghattas, Goutham Bojja, Junchao Xu, Gan Zhao, Claude C Warzecha, Marshall S Padilla, Rakan El-Mayta, Garima Dwivedi, Ying Xu, Andrew E Vaughan, James M Wilson, Drew Weissman, Michael J Mitchell
Fast and facile synthesis of amidine-incorporated degradable lipids for versatile mRNA delivery in vivo. Nature chemistry (2024)
Lulu Xue, Alex G Hamilton, Gan Zhao, Zebin Xiao, Rakan El-Mayta, Xuexiang Han, Ningqiang Gong, Xinhong Xiong, Junchao Xu, Christian G Figueroa-Espada, Sarah J Shepherd, Alvin J Mukalel, Mohamad Gabriel Alameh, Jiaxi Cui, Karin Wang, Andrew E Vaughan, Drew Weissman, Michael J Mitchell
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models. Nature communications 15 (1) (2024)
Lulu Xue, Alex G Hamilton, Gan Zhao, Zebin Xiao, Rakan El-Mayta, Xuexiang Han, Ningqiang Gong, Xinhong Xiong, Junchao Xu, Christian G Figueroa-Espada, Sarah J Shepherd, Alvin J Mukalel, Mohamad Gabriel Alameh, Jiaxi Cui, Karin Wang, Andrew E Vaughan, Drew Weissman, Michael J Mitchell
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models. Nature communications 15 (1) (2024)
Gan Zhao, Lulu Xue, Hannah C Geisler, Junchao Xu, Xinyuan Li, Michael J Mitchell, Andrew E Vaughan
Precision treatment of viral pneumonia through macrophage-targeted lipid nanoparticle delivery. Proceedings of the National Academy of Sciences of the United States of America 121 (7) (2024)
Kazushige Shiraishi, Michael P Morley, Dakota L Jones, Gan Zhao, Aaron I Weiner, Maria C Basil, Edward Cantu, Laura T Ferguson, Michele Oyster, Apoorva Babu, Yun Ying, Su Zhou, Shanru Li, Andrew E Vaughan, Edward E Morrisey
Airway epithelial cell identity and plasticity are constrained by Sox2 during lung homeostasis, tissue regeneration, and in human disease. NPJ Regenerative medicine 9 (1) (2024)
Gan Zhao, Lulu Xue, Aaron I Weiner, Ningqiang Gong, Stephanie Adams-Tzivelekidis, Joanna Wong, Maria E Gentile, Ana N Nottingham, Maria C Basal, Susan M Lin, Terren K Niethamer, Joshua M Diamond, Christian A Bermudez, Edward Cantu, Xuexiang Han, Yaqi Cao, Mohamad Gabriel Alameh, Drew Weissman, Edward E Morrisey, Michael J Mitchell, Andrew E Vaughan
TGF-βR2 signaling coordinates pulmonary vascular repair after viral injury in mice and human tissue. Science translational medicine 16 (732) (2024)
Gan Zhao, Maria E Gentile, Lulu Xue, Christopher V Cosgriff, Aaron I Weiner, Stephanie Adams-Tzivelekidis, Joanna Wong, Xinyuan Li, Sara Kass-Gergi, Nicolas P Holcomb, Maria C Basal, Kathleen M Stewart, Joseph D Planer, Edward Cantu, Jason D Christie, Maria M Crespo, Michael J Mitchell, Nuala J Meyer, Andrew E Vaughan
Vascular endothelial-derived SPARCL1 exacerbates viral pneumonia through pro-inflammatory macrophage activation. Nature communications 15 (1) (2024)
Luis R Rodriguez, Konstantinos-Dionysios Alysandratos, Jeremy Katzen, Aditi Murthy, Willy Roque Barboza, Yaniv Tomer, Rebeca Acin-Perez, Anton Petcherski, Kasey Minakin, Paige Carson, Swati Iyer, Katrina Chavez, Charlotte H Cooper, Apoorva Babu, Aaron I Weiner, Andrew E Vaughan, Zoltan Arany, Orian S Shirihai, Darrell N Kotton, Michael F Beers
Impaired AMPK Control of Alveolar Epithelial Cell Metabolism Promotes Pulmonary Fibrosis. bioRxiv : the preprint server for biology (2024)
Gan Zhao, Lulu Xue, Hannah C Geisler, Junchao Xu, Xinyuan Li, Michael J Mitchell, Andrew E Vaughan
Precision treatment of viral pneumonia through macrophage-targeted lipid nanoparticle delivery. Proceedings of the National Academy of Sciences of the United States of America 121 (7) (2024)
Gan Zhao, Maria E Gentile, Lulu Xue, Christopher V Cosgriff, Aaron I Weiner, Stephanie Adams-Tzivelekidis, Joanna Wong, Xinyuan Li, Sara Kass-Gergi, Nicolas P Holcomb, Maria C Basal, Kathleen M Stewart, Joseph D Planer, Edward Cantu, Jason D Christie, Maria M Crespo, Michael J Mitchell, Nuala J Meyer, Andrew E Vaughan
Vascular endothelial-derived SPARCL1 exacerbates viral pneumonia through pro-inflammatory macrophage activation. Nature communications 15 (1) (2024)
Ningqiang Gong, Wenqun Zhong, Mohamad Gabriel Alameh, Xuexiang Han, Lulu Xue, Rakan El-Mayta, Gan Zhao, Andrew E Vaughan, Zhiyuan Qin, Fengyuan Xu, Alex G Hamilton, Dongyoon Kim, Junchao Xu, Junhyong Kim, Xucong Teng, Jinghong Li, Xing-Jie Liang, Drew Weissman, Wei Guo, Michael J Mitchell
Tumour-derived small extracellular vesicles act as a barrier to therapeutic nanoparticle delivery. Nature materials (2024)
Gan Zhao, Maria E Gentile, Lulu Xue, Christopher V Cosgriff, Aaron I Weiner, Stephanie Adams-Tzivelekidis, Joanna Wong, Xinyuan Li, Sara Kass-Gergi, Nicolas P Holcomb, Maria C Basal, Kathleen M Stewart, Joseph D Planer, Edward Cantu, Jason D Christie, Maria M Crespo, Michael J Mitchell, Nuala J Meyer, Andrew E Vaughan
Vascular endothelial-derived SPARCL1 exacerbates viral pneumonia through pro-inflammatory macrophage activation. Nature communications 15 (1) (2024)
Gan Zhao, Lulu Xue, Aaron I Weiner, Ningqiang Gong, Stephanie Adams-Tzivelekidis, Joanna Wong, Maria E Gentile, Ana N Nottingham, Maria C Basal, Susan M Lin, Terren K Niethamer, Joshua M Diamond, Christian A Bermudez, Edward Cantu, Xuexiang Han, Yaqi Cao, Mohamad Gabriel Alameh, Drew Weissman, Edward E Morrisey, Michael J Mitchell, Andrew E Vaughan
TGF-βR2 signaling coordinates pulmonary vascular repair after viral injury in mice and human tissue. Science translational medicine 16 (732) (2024)
Dakota L Jones, Michael P Morley, Xinyuan Li, Yun Ying, Fabian L Cardenas-Diaz, Shanru Li, Su Zhou, Sarah E Schaefer, Ullas V Chembazhi, Ana Nottingham, Susan Lin, Edward Cantu, Joshua M Diamond, Maria C Basil, Andrew E Vaughan, Edward E Morrisey
An injury-induced tissue niche shaped by mesenchymal plasticity coordinates the regenerative and disease response in the lung. bioRxiv : the preprint server for biology (2024)
Kazushige Shiraishi, Michael P Morley, Dakota L Jones, Gan Zhao, Aaron I Weiner, Maria C Basil, Edward Cantu, Laura T Ferguson, Michele Oyster, Apoorva Babu, Yun Ying, Su Zhou, Shanru Li, Andrew E Vaughan, Edward E Morrisey
Airway epithelial cell identity and plasticity are constrained by Sox2 during lung homeostasis, tissue regeneration, and in human disease. NPJ Regenerative medicine 9 (1) (2024)
Gan Zhao, Lulu Xue, Hannah C Geisler, Junchao Xu, Xinyuan Li, Michael J Mitchell, Andrew E Vaughan
Precision treatment of viral pneumonia through macrophage-targeted lipid nanoparticle delivery. Proceedings of the National Academy of Sciences of the United States of America 121 (7) (2024)
Kazushige Shiraishi, Michael P Morley, Dakota L Jones, Gan Zhao, Aaron I Weiner, Maria C Basil, Edward Cantu, Laura T Ferguson, Michele Oyster, Apoorva Babu, Yun Ying, Su Zhou, Shanru Li, Andrew E Vaughan, Edward E Morrisey
Airway epithelial cell identity and plasticity are constrained by Sox2 during lung homeostasis, tissue regeneration, and in human disease. NPJ Regenerative medicine 9 (1) (2024)
Lulu Xue, Alex G Hamilton, Gan Zhao, Zebin Xiao, Rakan El-Mayta, Xuexiang Han, Ningqiang Gong, Xinhong Xiong, Junchao Xu, Christian G Figueroa-Espada, Sarah J Shepherd, Alvin J Mukalel, Mohamad Gabriel Alameh, Jiaxi Cui, Karin Wang, Andrew E Vaughan, Drew Weissman, Michael J Mitchell
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models. Nature communications 15 (1) (2024)
Gan Zhao, Lulu Xue, Aaron I Weiner, Ningqiang Gong, Stephanie Adams-Tzivelekidis, Joanna Wong, Maria E Gentile, Ana N Nottingham, Maria C Basal, Susan M Lin, Terren K Niethamer, Joshua M Diamond, Christian A Bermudez, Edward Cantu, Xuexiang Han, Yaqi Cao, Mohamad Gabriel Alameh, Drew Weissman, Edward E Morrisey, Michael J Mitchell, Andrew E Vaughan
TGF-βR2 signaling coordinates pulmonary vascular repair after viral injury in mice and human tissue. Science translational medicine 16 (732) (2024)
Xuexiang Han, Junchao Xu, Ying Xu, Mohamad Gabriel Alameh, Lulu Xue, Ningqiang Gong, Rakan El-Mayta, Rohan Palanki, Claude C Warzecha, Gan Zhao, Andrew E Vaughan, James M Wilson, Drew Weissman, Michael J Mitchell
In situ combinatorial synthesis of degradable branched lipidoids for systemic delivery of mRNA therapeutics and gene editors. Nature communications 15 (1) (2024)
Gan Zhao, Lulu Xue, Aaron I Weiner, Ningqiang Gong, Stephanie Adams-Tzivelekidis, Joanna Wong, Maria E Gentile, Ana N Nottingham, Maria C Basal, Susan M Lin, Terren K Niethamer, Joshua M Diamond, Christian A Bermudez, Edward Cantu, Xuexiang Han, Yaqi Cao, Mohamad Gabriel Alameh, Drew Weissman, Edward E Morrisey, Michael J Mitchell, Andrew E Vaughan
TGF-βR2 signaling coordinates pulmonary vascular repair after viral injury in mice and human tissue. Science translational medicine 16 (732) (2024)
Gan Zhao, Lulu Xue, Hannah C Geisler, Junchao Xu, Xinyuan Li, Michael J Mitchell, Andrew E Vaughan
Precision treatment of viral pneumonia through macrophage-targeted lipid nanoparticle delivery. Proceedings of the National Academy of Sciences of the United States of America 121 (7) (2024)
Lulu Xue, Alex G Hamilton, Gan Zhao, Zebin Xiao, Rakan El-Mayta, Xuexiang Han, Ningqiang Gong, Xinhong Xiong, Junchao Xu, Christian G Figueroa-Espada, Sarah J Shepherd, Alvin J Mukalel, Mohamad Gabriel Alameh, Jiaxi Cui, Karin Wang, Andrew E Vaughan, Drew Weissman, Michael J Mitchell
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models. Nature communications 15 (1) (2024)
Gan Zhao, Lulu Xue, Aaron I Weiner, Ningqiang Gong, Stephanie Adams-Tzivelekidis, Joanna Wong, Maria E Gentile, Ana N Nottingham, Maria C Basal, Susan M Lin, Terren K Niethamer, Joshua M Diamond, Christian A Bermudez, Edward Cantu, Xuexiang Han, Yaqi Cao, Mohamad Gabriel Alameh, Drew Weissman, Edward E Morrisey, Michael J Mitchell, Andrew E Vaughan
TGF-βR2 signaling coordinates pulmonary vascular repair after viral injury in mice and human tissue. Science translational medicine 16 (732) (2024)
Lulu Xue, Alex G Hamilton, Gan Zhao, Zebin Xiao, Rakan El-Mayta, Xuexiang Han, Ningqiang Gong, Xinhong Xiong, Junchao Xu, Christian G Figueroa-Espada, Sarah J Shepherd, Alvin J Mukalel, Mohamad Gabriel Alameh, Jiaxi Cui, Karin Wang, Andrew E Vaughan, Drew Weissman, Michael J Mitchell
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models. Nature communications 15 (1) (2024)
Kazushige Shiraishi, Michael P Morley, Dakota L Jones, Gan Zhao, Aaron I Weiner, Maria C Basil, Edward Cantu, Laura T Ferguson, Michele Oyster, Apoorva Babu, Yun Ying, Su Zhou, Shanru Li, Andrew E Vaughan, Edward E Morrisey
Airway epithelial cell identity and plasticity are constrained by Sox2 during lung homeostasis, tissue regeneration, and in human disease. NPJ Regenerative medicine 9 (1) (2024)
Gan Zhao, Maria E Gentile, Lulu Xue, Christopher V Cosgriff, Aaron I Weiner, Stephanie Adams-Tzivelekidis, Joanna Wong, Xinyuan Li, Sara Kass-Gergi, Nicolas P Holcomb, Maria C Basal, Kathleen M Stewart, Joseph D Planer, Edward Cantu, Jason D Christie, Maria M Crespo, Michael J Mitchell, Nuala J Meyer, Andrew E Vaughan
Vascular endothelial-derived SPARCL1 exacerbates viral pneumonia through pro-inflammatory macrophage activation. Nature communications 15 (1) (2024)
Dakota L Jones, Michael P Morley, Xinyuan Li, Yun Ying, Fabian L Cardenas-Diaz, Shanru Li, Su Zhou, Sarah E Schaefer, Ullas V Chembazhi, Ana Nottingham, Susan Lin, Edward Cantu, Joshua M Diamond, Maria C Basil, Andrew E Vaughan, Edward E Morrisey
An injury-induced tissue niche shaped by mesenchymal plasticity coordinates the regenerative and disease response in the lung. bioRxiv : the preprint server for biology (2024)
Lulu Xue, Alex G Hamilton, Gan Zhao, Zebin Xiao, Rakan El-Mayta, Xuexiang Han, Ningqiang Gong, Xinhong Xiong, Junchao Xu, Christian G Figueroa-Espada, Sarah J Shepherd, Alvin J Mukalel, Mohamad Gabriel Alameh, Jiaxi Cui, Karin Wang, Andrew E Vaughan, Drew Weissman, Michael J Mitchell
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models. Nature communications 15 (1) (2024)
Gan Zhao, Lulu Xue, Aaron I Weiner, Ningqiang Gong, Stephanie Adams-Tzivelekidis, Joanna Wong, Maria E Gentile, Ana N Nottingham, Maria C Basal, Susan M Lin, Terren K Niethamer, Joshua M Diamond, Christian A Bermudez, Edward Cantu, Xuexiang Han, Yaqi Cao, Mohamad Gabriel Alameh, Drew Weissman, Edward E Morrisey, Michael J Mitchell, Andrew E Vaughan
TGF-βR2 signaling coordinates pulmonary vascular repair after viral injury in mice and human tissue. Science translational medicine 16 (732) (2024)
Dakota L Jones, Michael P Morley, Xinyuan Li, Yun Ying, Fabian L Cardenas-Diaz, Shanru Li, Su Zhou, Sarah E Schaefer, Ullas V Chembazhi, Ana Nottingham, Susan Lin, Edward Cantu, Joshua M Diamond, Maria C Basil, Andrew E Vaughan, Edward E Morrisey
An injury-induced tissue niche shaped by mesenchymal plasticity coordinates the regenerative and disease response in the lung. bioRxiv : the preprint server for biology (2024)
Lulu Xue, Alex G Hamilton, Gan Zhao, Zebin Xiao, Rakan El-Mayta, Xuexiang Han, Ningqiang Gong, Xinhong Xiong, Junchao Xu, Christian G Figueroa-Espada, Sarah J Shepherd, Alvin J Mukalel, Mohamad Gabriel Alameh, Jiaxi Cui, Karin Wang, Andrew E Vaughan, Drew Weissman, Michael J Mitchell
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models. Nature communications 15 (1) (2024)
Xuexiang Han, Junchao Xu, Ying Xu, Mohamad Gabriel Alameh, Lulu Xue, Ningqiang Gong, Rakan El-Mayta, Rohan Palanki, Claude C Warzecha, Gan Zhao, Andrew E Vaughan, James M Wilson, Drew Weissman, Michael J Mitchell
In situ combinatorial synthesis of degradable branched lipidoids for systemic delivery of mRNA therapeutics and gene editors. Nature communications 15 (1) (2024)
Xuexiang Han, Junchao Xu, Ying Xu, Mohamad Gabriel Alameh, Lulu Xue, Ningqiang Gong, Rakan El-Mayta, Rohan Palanki, Claude C Warzecha, Gan Zhao, Andrew E Vaughan, James M Wilson, Drew Weissman, Michael J Mitchell
In situ combinatorial synthesis of degradable branched lipidoids for systemic delivery of mRNA therapeutics and gene editors. Nature communications 15 (1) (2024)
Gan Zhao, Maria E Gentile, Lulu Xue, Christopher V Cosgriff, Aaron I Weiner, Stephanie Adams-Tzivelekidis, Joanna Wong, Xinyuan Li, Sara Kass-Gergi, Nicolas P Holcomb, Maria C Basal, Kathleen M Stewart, Joseph D Planer, Edward Cantu, Jason D Christie, Maria M Crespo, Michael J Mitchell, Nuala J Meyer, Andrew E Vaughan
Vascular endothelial-derived SPARCL1 exacerbates viral pneumonia through pro-inflammatory macrophage activation. Nature communications 15 (1) (2024)
Gan Zhao, Maria E Gentile, Lulu Xue, Christopher V Cosgriff, Aaron I Weiner, Stephanie Adams-Tzivelekidis, Joanna Wong, Xinyuan Li, Sara Kass-Gergi, Nicolas P Holcomb, Maria C Basal, Kathleen M Stewart, Joseph D Planer, Edward Cantu, Jason D Christie, Maria M Crespo, Michael J Mitchell, Nuala J Meyer, Andrew E Vaughan
Vascular Endothelial-derived SPARCL1 Exacerbates Viral Pneumonia Through Pro-Inflammatory Macrophage Activation. bioRxiv : the preprint server for biology (2023)
Justinn Barr, Maria Elena Gentile, Sunyoung Lee, Maya E Kotas, Maria Fernanda de Mello Costa, Nicolas P Holcomb, Abigail Jaquish, Gargi Palashikar, Marcella Soewignjo, Margaret McDaniel, Ichiro Matsumoto, Robert Margolskee, Jakob Von Moltke, Noam A Cohen, Xin Sun, Andrew E Vaughan
Injury-induced pulmonary tuft cells are heterogenous, arise independent of key Type 2 cytokines, and are dispensable for dysplastic repair. eLife 11 (2022)
Laertis Ikonomou, Mattias Magnusson, Ruben Dries, Erica L Herzog, Robert Edward Hynds, Zea Borok, Jin-Ah Park, Steven Skolasinski, Janette Kay Burgess, Leigh Turner, Sarah M Mojarad, John E Mahoney, Thomas Lynch, Mareike Lehmann, Victor J Thannickal, Jaime Lynn Hook, Andrew E Vaughan, Evan T Hoffman, Daniel J Weiss, Amy L Ryan
Stem cells, cell therapies, and bioengineering in lung biology and disease 2021. American journal of physiology. Lung cellular and molecular physiology 323 (3) (2022)
Sara Kass-Gergi, Andrew E Vaughan
Alveolar Repair after Viral Injury: A Tale of Two Cell Types. American journal of respiratory cell and molecular biology 67 (3) (2022)
L K Metthew Lam, Sophia Murphy, Dimitra Kokkinaki, Alessandro Venosa, Scott Sherrill-Mix, Carla Casu, Stefano Rivella, Aaron I Weiner, Jeongho Park, Sunny Shin, Andrew E Vaughan, Beatrice H Hahn, Audrey R Odom John, Nuala J Meyer, Christopher A Hunter, G Scott Worthen, Nilam S Mangalmurti
DNA binding to TLR9 expressed by red blood cells promotes innate immune activation and anemia. Science translational medicine 13 (616) (2021)
Gan Zhao, Aaron I Weiner, Katherine M Neupauer, Maria Fernanda de Mello Costa, Gargi Palashikar, Stephanie Adams-Tzivelekidis, Nilam S Mangalmurti, Andrew E Vaughan
Regeneration of the pulmonary vascular endothelium after viral pneumonia requires COUP-TF2. Science advances 6 (48) (2020)
Nilam S Mangalmurti, John P Reilly, Douglas B Cines, Nuala J Meyer, Christopher A Hunter, Andrew E Vaughan
COVID-19-associated Acute Respiratory Distress Syndrome Clarified: A Vascular Endotype? American journal of respiratory and critical care medicine 202 (5) (2020)
S R Jackson, M F D M Costa, C F Pastore, G Zhao, A I Weiner, S Adams, G Palashikar, K Quansah, K Hankenson, D R Herbert, Andrew E Vaughan
R-spondin 2 mediates neutrophil egress into the alveolar space through increased lung permeability. BMC research notes 13 (1) (2020)
Aaron I Weiner, Sergio R Jackson, Gan Zhao, Kwaku K Quansah, Joseph N Farshchian, Katherine M Neupauer, Elizabeth Q Littauer, Andrew J Paris, Derek C Liberti, G Scott Worthen, Edward E Morrisey, Andrew E Vaughan
Mesenchyme-free expansion and transplantation of adult alveolar progenitor cells: steps toward cell-based regenerative therapies. NPJ Regenerative medicine 4 (2019)
Chetan K Rane, Sergio R Jackson, Christopher F Pastore, Gan Zhao, Aaron I Weiner, Neil N Patel, De'Broski R Herbert, Noam A Cohen, Andrew E Vaughan
Development of solitary chemosensory cells in the distal lung after severe influenza injury. American journal of physiology. Lung cellular and molecular physiology 316 (6) (2019)