Quantification of huntingtin protein species in Huntington's disease patient leukocytes using optimised electrochemiluminescence immunoassays.
Davina J Hensman MossNicola RobertsonRuth FarmerRachael I ScahillSalman HaiderMichela A TessariGeraldine FlynnDavid F FischerEdward J WildDouglas MacdonaldSarah J TabriziPublished in: PloS one (2017)
The assays were sensitive and accurate. We confirm our previous findings that mHTT increases with advancing disease stage in patient PBMCs, this time using a simple collection protocol and scalable assay.