Polyclonal B-cell lymphocytosis in English bulldogs.

Emily D Rout A Russell MooreRobert C BurnettJulia D LabadieKelly L HughesPaul A NavinJanna A YoshimotoPaul R AveryAnne C Avery

Published in: Journal of veterinary internal medicine (2020)

Polyclonal B-cell lymphocytosis in English bulldogs is characterized by low B-cell class II MHC and CD25 expression, splenomegaly and hyperglobulinemia consisting of increased IgA ± IgM. We hypothesize that this syndrome has a genetic basis.

Keyphrases

poor prognosis
binding protein
copy number
nk cells