Trimming the fat: is there a health economic case for the use of new lipid-lowering drugs in chronic kidney disease? A scoping review.
Alexandra GallagherBlaise AgrestaBrendan SmythMeg JardineCharles Joseph FerroRachael Lisa MortonPublished in: Clinical kidney journal (2021)
This review found PCSK9is were moderately cost-effective in populations with high cardiovascular risk. People with CKD were included as an undifferentiated subpopulation in the primary studies, but application of these findings to CKD-specific populations should be interpreted with caution. There is insufficient evidence for a health economic case to support novel lipid-lowering therapies for advanced CKD.