Exosomes Derived from Human Amniotic Fluid Mesenchymal Stem Cells Preserve Microglia and Neuron Cells from Aβ.

Manuela ZavattiMartina GattiFrancesca BerettiAntonella SolaTullia Maraldi

Published in: International journal of molecular sciences (2022)

We demonstrated that hAFSC-exo mitigated an inflammatory injury caused by microglia and significantly recovered the neurotoxicity, suggesting that hAFSC-exo may be a potential therapeutic agent for inflammation-related neurological conditions, including AD.

Keyphrases

mesenchymal stem cells
umbilical cord
oxidative stress
inflammatory response
endothelial cells
neuropathic pain
bone marrow
induced pluripotent stem cells
stem cells
pluripotent stem cells
cell therapy
spinal cord injury
brain injury