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A new aliphatic ester of hydroxysalicylic acid from fermented Carica papaya L. preparation with a potential hair growth stimulating activity.

Ahmed AshourYhiya AmenToshinori NakagawaYasuharu NiwaAmira MiraKoichiro OhnukiShinki MurakamiMitsuko ImaoKuniyoshi Shimizu
Published in: Natural product research (2018)
An aliphatic ester of hydroxysalicylic acid (6), reported for the first time from a natural source in addition to five known compounds were isolated from the fermented Carica papaya L. preparation, a commercialized functional food. The known compounds were identified as 5-hydroxymethylfurfuraldehyde (1), trans-caffeic acid (2), butyl 4-hydroxybenzoate (butylparaben) (3), lycopene (4), benzyl isothiocyanate (5). Compounds 1 and 3 were reported for the first time from Papaya fruits through this study. The new compound showed a moderate antioxidant activity and a potent hair growth stimulating activity in vitro.
Keyphrases
  • human health
  • molecularly imprinted
  • high intensity
  • lactic acid
  • risk assessment