Therapeutic Effect and Mechanism of Negative Pressure Wound Therapy with Huoxue Shengji Decoction Instillation for Chronic Skin Ulcers.
Sunfeng PanLie XiongZhenjun WangYujuan SuGaofeng FangMinda ZhuJing WangHanqiang ShiShi-Hui ZhuYanbo ShiPublished in: Evidence-based complementary and alternative medicine : eCAM (2022)
HXSJ decoction can enhance the expression of VEGF and VEGFR-2 and promote the proliferation of HUVECs. Treatment with NWPT with HXSJ decoction instillation can further reduce the wound cavity volume; meanwhile, it can promote blood vessel formation in ulcer wounds, thus accelerating the healing of CSUs.