MRI-based synthetic CT: a new method for structural damage assessment in the spine in patients with axial spondyloarthritis - a comparison with low-dose CT and radiography.
Simone Tromborg WillesenAnna Enevold Fløistrup E F HadsbjergJakob Møllenbach MøllerNora VladimirovaBimal M K VoraSengül SevenSusanne Juhl PedersenMikkel ØstergaardPublished in: Annals of the rheumatic diseases (2024)
With ldCT as reference standard, MRI-based sCT of the spine showed very high specificity and a sensitivity much higher than radiography, despite limited reader training. sCT could become highly valuable for detecting/monitoring structural spine damage in axSpA, not the least in clinical trials.
Keyphrases
- contrast enhanced
- image quality
- low dose
- magnetic resonance imaging
- computed tomography
- clinical trial
- dual energy
- magnetic resonance
- oxidative stress
- diffusion weighted imaging
- ankylosing spondylitis
- positron emission tomography
- randomized controlled trial
- cone beam computed tomography
- systemic lupus erythematosus
- phase ii