Differentially Expressed Circular RNAs in Peripheral Blood Mononuclear Cells of Patients with Parkinson's Disease.

Stylianos Ravanidis Anastasia BougeaDimitra KarampatsiNikolaos PapagiannakisMatina ManiatiLeonidas Stefanis Epaminondas Doxakis

Published in: Movement disorders : official journal of the Movement Disorder Society (2021)

This is the first study that identifies specific circRNAs that may serve as diagnostic biomarkers for PD. Because they are highly expressed in the brain and are derived from genes with essential brain functions, they may also hint on the PD pathways affected. © 2021 Biomedical Research Foundation, Academy of Athens. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

Keyphrases

resting state
genome wide
white matter
functional connectivity
cerebral ischemia
randomized controlled trial
gene expression
dna methylation
multiple sclerosis