Dietary nitrate supplementation to enhance exercise capacity in hypoxic COPD: EDEN-OX, a double-blind, placebo-controlled, randomised cross-over study.
Matthew J PavittAdam LewisSara C ButteryBernadette O FernandezMonika Mikus-LelinskaWinston A S BanyaMartin FeelischMichael I PolkeyNicholas S HopkinsonPublished in: Thorax (2021)
Acute dietary nitrate supplementation increases exercise endurance in patients with COPD who require supplemental oxygen.Trial registration number ISRCTN14888729.
Keyphrases
- high intensity
- placebo controlled
- study protocol
- chronic obstructive pulmonary disease
- double blind
- clinical trial
- phase iii
- resistance training
- phase ii
- nitric oxide
- lung function
- open label
- drinking water
- physical activity
- liver failure
- skeletal muscle
- respiratory failure
- randomized controlled trial
- drug induced
- squamous cell carcinoma
- cystic fibrosis
- air pollution
- phase ii study