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Human leucocyte antigen association of patients with Stevens-Johnson syndrome/toxic epidermal necrolysis with severe ocular complications in Han Chinese.

Kevin Sheng-Kai MaWen Hung ChungYi-Jen HsuehShin-Yi ChenKatsushi TokunagaShigeru KinoshitaDavid H K MaMayumi Ueta
Published in: The British journal of ophthalmology (2021)
The HLA-A*02:07 and HLA-B*46:01 alleles were significantly associated with SOCs among Han Chinese patients with CM-SJS/TEN. These findings demonstrate the genetic diversity in SJS pathogenesis among different ethnic groups.
Keyphrases
  • genetic diversity
  • endothelial cells
  • induced pluripotent stem cells
  • early onset
  • risk factors
  • pluripotent stem cells
  • case report
  • drug induced
  • optic nerve
  • optical coherence tomography