Covalent capture and electrochemical quantification of pathogenic E. coli.
Sarah H KlassLaura E SofenZachary F HallbergTahoe A FialaAlexandra V RamseyNicholas S DolanMatthew B FrancisAriel L FurstPublished in: Chemical communications (Cambridge, England) (2021)
Pathogenic E. coli pose a significant threat to public health, as strains of this species cause both foodborne illnesses and urinary tract infections. Using a rapid bioconjugation reaction, we selectively capture E. coli at a disposable gold electrode from complex solutions and accurately quantify the pathogenic microbes using electrochemical impedance spectroscopy.