Ontogeny of human IgE-expressing B cells and plasma cells.
Faruk RamadaniH BowenN UptonP S HobsonY-C ChanJ-B ChenT W ChangJ M McDonnellB J SuttonD J FearH J GouldPublished in: Allergy (2016)
Generation of IgE+ PCs from tonsil GC B cells occurs mainly via sequential switching from IgG. The mIgEL /mIgES ratio may be implicated in survival of IgE+ B cells during PC differentiation and allergic disease.