Antihyperglycemic activity of 14-deoxy, 11, 12-didehydro andrographolide on streptozotocin-nicotinamide induced type 2 diabetic rats.

Nagalakshmi KamarajKadhirmathiyan VelumaniAjay GuruPraveen Kumar Issac

Published in: Molecular biology reports (2023)

Overall, the finding indicates that 14-deoxy, 11, 12-didehydro andrographolide exhibited antihyperglycemic activity by modulating the expression of insulin cascades.

Keyphrases

diabetic rats
oxidative stress
type diabetes
poor prognosis
signaling pathway
endothelial cells