Benzodiazepine administration patterns before escalation to second-line medications in pediatric refractory convulsive status epilepticus.
Theodore SheehanMarta Amengual-GualAlejandra VasquezNicholas S AbendAnne AndersonBrian AppavuRavindra AryaCristina Barcia AguilarJ Nicholas BrentonJessica L CarpenterKevin E ChapmanJustice ClarkRaquel Farias-MoellerWilliam Davis GaillardMarina Gaínza-LeinTracy A GlauserJoshua L GoldsteinHoward P GoodkinRejean M GuerrieroLinda HuhMichele JacksonKush KapurRobert KahoudYi-Chen LaiTiffani L McDonoughMohamad A MikatiLindsey A MorganEdward J NovotnyAdam P OstendorfEric T PayneKatrina PearisoJuan PiantinoLatania ReeceJames J RivielloTristan T SandsKumar SannagowdaraRenée A ShellhaasGarnett SmithRobert C TaskerDmitry TchapyjnikovAlexis A TopjianMark S WainwrightAngus WilfongKorwyn WilliamsBo ZhangTobias Loddenkempernull nullPublished in: Epilepsia (2021)
Failure to escalate from BZDs to non-BZD ASMs occurs mainly in out-of-hospital rSE onset. Delays in the implementation of medical guidelines may be reduced by initiating treatment before hospital arrival and facilitating a transition to non-BZD ASMs after two BZD doses during handoffs between prehospital and in-hospital settings.