Activation of the Alternate Renin-Angiotensin System Correlates with the Clinical Status in Human Cirrhosis and Corrects Post Liver Transplantation.
Stephen CaseyRobert SchierwagenKai Yan MakSabine KleinFrank UschnerChristian JansenMichael PraktiknjoCarsten MeyerDaniel ThomasChandana HerathRobert JonesJonel TrebickaPeter AngusPublished in: Journal of clinical medicine (2019)
In human cirrhosis, the alternate RAS is markedly upregulated and the activation of this system is associated strongly with features of the hyperdynamic circulation in advanced human cirrhosis.