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Phase 1, open-label, dose-escalation study on the safety, pharmacokinetics, and preliminary efficacy of intravenous Coxsackievirus A21 (V937), with or without pembrolizumab, in patients with advanced solid tumors.

Charles M RudinHardev S PandhaMatthew ZibelmanWallace L AkerleyKevin J HarringtonDaphne DayAndrew G HillSteven J O'DayTimothy D ClayGavin M WrightRoss R JennensDavid E GerberJonathan E RosenbergChristy RalphDavid C CampbellBrendan D CurtiJaime R MerchanYixin RenEmmett V SchmidtLisa GuttmanSumati V Gupta
Published in: Journal for immunotherapy of cancer (2023)
NCT02043665.
Keyphrases
  • open label
  • clinical trial
  • phase ii
  • high dose
  • phase iii
  • study protocol
  • advanced non small cell lung cancer
  • randomized controlled trial
  • squamous cell carcinoma
  • radiation therapy
  • rectal cancer