The influence of maternal prepregnancy weight and gestational weight gain on the umbilical cord blood metabolome: a case-control study.
Xianxian YuanYuru MaJia WangYan ZhaoWei ZhengRuihua YangLirui ZhangXin YanGuanghui LiPublished in: BMC pregnancy and childbirth (2024)
Prepregnancy overweight and obesity affected the fetal steroid hormone biosynthesis pathway, while excessive GWG affected fetal fatty acid metabolism. This emphasizes the importance of preconception weight loss and maintaining an appropriate GWG, which are beneficial for the long-term metabolic health of offspring.
Keyphrases
- weight gain
- weight loss
- birth weight
- umbilical cord
- mesenchymal stem cells
- body mass index
- fatty acid
- bariatric surgery
- roux en y gastric bypass
- healthcare
- public health
- gastric bypass
- mental health
- high fat diet
- health information
- glycemic control
- bone marrow
- physical activity
- pregnancy outcomes
- metabolic syndrome
- human health
- type diabetes
- pregnant women