Enamel matrix derivative does not affect osteoclast formation or bone resorption in cultures of mouse bone marrow macrophages or human monocytes.
Susanne LindquistCatrine IsehedAnita LiePernilla LundbergPublished in: Acta odontologica Scandinavica (2022)
The results on natural bone matrix contradict a direct effect of EMD on osteoclast precursor cells.