Ultrasound-guided Targeted vs. Regional Flooding: A Comparative Study for Improving the Clinical Outcome in Soft Tissue Filler Vascular Adverse Event Management.

Despite its limitations in study design, this retrospectively evaluated case series revealed that the ultrasound guided targeted protocol utilized less hyaluronidase material and restored faster clinically visible symptoms. The effect of this protocol is best explained by the perforasome concept which will need to be investigated further in future studies.