Six-Month Angiographic and Clinical Outcomes of Therapeutic Ultrasound Pretreatment Associated With Plain Balloon Angioplasty for Below-the-Knee Lesions in Patients With Critical Limb Ischemia: A Prospective, Single-Center Pilot Study.
Costantino Del GiudiceRoberto GandiniPublished in: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists (2019)
This pilot trial with a small number of patients suggests that low-frequency, high-intensity ultrasound energy delivery followed by plain balloon angioplasty is a safe approach to treat infrapopliteal atherosclerotic lesions. Angiographically-documented results at 6 months indicate a potential for this combined therapy in the treatment of CLI patients with calcified BTK lesions. Further studies on a larger randomized cohort are needed to confirm these positive clinical outcomes.
Keyphrases
- high intensity
- end stage renal disease
- magnetic resonance imaging
- ejection fraction
- chronic kidney disease
- newly diagnosed
- resistance training
- double blind
- tyrosine kinase
- ultrasound guided
- randomized controlled trial
- risk assessment
- bone marrow
- phase iii
- placebo controlled
- computed tomography
- climate change
- study protocol
- smoking cessation