MicroRNA-210-3p is transcriptionally upregulated by hypoxia induction and thus promoting EMT and chemoresistance in glioma cells.

Hong LiuChangjin ChenJinhao ZengZi-Yi ZhaoQiongying Hu

Published in: PloS one (2021)

These results help to reveal the potential regulatory mechanisms of hypoxia-induced miR-210-3p expression that affect malignant behaviors and chemoresistance via TGF-β upregulation in glioma cells.

Keyphrases

poor prognosis
epithelial mesenchymal transition
transforming growth factor
long non coding rna
cell proliferation
transcription factor
endothelial cells
cancer stem cells
single cell
signaling pathway
gene expression