Clinical importance of the lncRNA NEAT1 in cancer patients treated with immune checkpoint inhibitors.

Joseph S Toker J Bryan Iorgulescu Alexander L Ling Genaro Rodriguez Villa Josephina A M A Gadet Laxmi Parida Gad A Getz Catherine J Wu David A Reardon E Antonio Chiocca Marco Mineo

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)

These findings suggest an association between NEAT1 expression and patient response to anti-PD-1/PD-L1 therapy in melanoma and GBM and have important implications for the role of lncRNAs in the tumor microenvironment.

Keyphrases

papillary thyroid
poor prognosis
squamous cell
case report
long non coding rna
stem cells
binding protein
lymph node metastasis
long noncoding rna
cell therapy
network analysis
skin cancer
genome wide analysis
smoking cessation