Combination of GM CSF and carbapenem is superior to carbapenem monotherapy in difficult to treat SBP:A randomized controlled trial.
Vikash PrakashVinod AroraAnkur JindalRakhi MaiwallShiv Kumar SarinPublished in: Liver international : official journal of the International Association for the Study of the Liver (2023)
Addition of GM-CSF to meropenem significantly improves response rates in DTT SBP patients within 48 hours. Early use of GMCSF modulates host immune response, enhance antibiotic response with higher SBP resolution. Use of GMCSF needs to be considered in combating difficult SBP in cirrhosis patients.