Incidence of Hepatocellular Carcinoma in Primary Biliary Cholangitis: A Systematic Review and Meta-Analysis.

Yamini NatarajanAylin TanselParth PatelKingsley EmologuRicha ShuklaZeeshan QureshiHashem B El-SeragAaron P ThriftFasiha Kanwal

Published in: Digestive diseases and sciences (2020)

Cirrhosis is the strongest risk factor for HCC in patients with PBC. Male gender was also a risk factor. Our meta-analysis supports current recommendations of HCC surveillance in patients with PBC cirrhosis. Further studies are needed to evaluate risk factors in this population.

Keyphrases

risk factors
systematic review
case control
public health
meta analyses
mental health
clinical practice
randomized controlled trial
ulcerative colitis