COVID-19 PCR: frequency of internal control inhibition in clinical practice.

Alessandro Cumaru PasqualottoAmanda L Seus

Published in: Access microbiology (2023)

This study showed a low percentage of inhibition using RNase P as an internal control in COVID-19 PCRs using the CDC protocol, thus proving the effectiveness of this protocol for identification of SARS-CoV-2 in clinical samples. Re-extraction was efficacious for samples that showed little or no fluorescence for the RNase P gene.

Keyphrases

sars cov
randomized controlled trial
coronavirus disease
clinical practice
respiratory syndrome coronavirus
systematic review
genome wide
copy number
single molecule