Diagnostic value of BRCA1-associated protein-1, glucose transporter-1 and desmin expression in the discrimination between reactive mesothelial proliferation and malignant mesothelioma in tissues and effusions.

Sevgen Celik OnderEce ÖzogulDeniz KoksalSevinc Sarinc UlasliPinar FiratSalih Emri

Published in: Cytopathology : official journal of the British Society for Clinical Cytology (2019)

BAP1, GLUT-1 and desmin are useful markers in the discrimination between reactive and malignant mesothelial proliferations. BAP1 loss seems to be diagnostic for mesotheliomas both in biopsy and cytology samples.

Keyphrases

fine needle aspiration
ultrasound guided
poor prognosis
high glucose
signaling pathway
gene expression
high grade
binding protein
type diabetes
glycemic control