Diabetes mellitus increases risk of adverse drug reactions and death in hospitalised older people: the SENATOR trial.
Anagha ChinmayeeSelvarani SubbarayanPhyo Kyaw MyintAntonio CherubiniAlfonso J Cruz-JentoftMirko PetrovicAdalsteinn GudmundssonStephen ByrneDenis O'MahonyRoy Louis SoizaPublished in: European geriatric medicine (2023)
Older multimorbid people with diabetes presenting to hospital with acute illness have significantly more ADRs than those without, and a significantly higher mortality that is mediated by medication-associated AKI and poorer renal function.
Keyphrases
- adverse drug
- drug induced
- glycemic control
- liver failure
- type diabetes
- electronic health record
- acute kidney injury
- cardiovascular disease
- study protocol
- respiratory failure
- cardiovascular events
- phase iii
- clinical trial
- physical activity
- phase ii
- community dwelling
- middle aged
- risk factors
- aortic dissection
- healthcare
- randomized controlled trial
- insulin resistance
- metabolic syndrome