Transcriptomic signatures reveal immune dysregulation in human diabetic and idiopathic gastroparesis.

Madhusudan GroverSimon J GibbonsAsha A NairCheryl E BernardAdeel S ZubairSeth T EisenmanLaura A WilsonLaura MirielPankaj J PasrichaHenry P ParkmanIrene SarosiekRichard W McCallumKenneth L KochThomas L AbellWilliam J SnapeBraden KuoRobert J ShulmanTravis J McKenzieTodd A KelloggMichael L KendrickJames TonasciaFrank A HamiltonGianrico Farrugianull null

Published in: BMC medical genomics (2018)

Diabetic and idiopathic gastroparesis have both unique and overlapping transcriptomic signatures. Innate immune signaling likely plays a central role in pathogenesis of human gastroparesis.

Keyphrases

endothelial cells
innate immune
single cell
type diabetes
induced pluripotent stem cells
pluripotent stem cells
rna seq
wound healing
gene expression