Predictive role of HER2-status on the effectiveness of endocrine adjuvant treatment in postmenopausal breast cancer patients: a population-based cohort study.

Aglaia SchizaDavide MauriIrma Fredrikssonnull Anna-Karin WennstigAntonios Valachis

Published in: Breast cancer research and treatment (2020)

Our study results, based on propensity-matched cohorts, did not support any predictive value of HER2-status on endocrine therapy in postmenopausal BC patients. AI-based ET remains the treatment of choice for postmenopausal BC patients with HR-positive disease in the modern era of HER2-directed therapy irrespective of HER2-status.

Keyphrases

bone mineral density
end stage renal disease
randomized controlled trial
ejection fraction
systematic review
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
machine learning
combination therapy
patient reported outcomes
deep learning
cell therapy
patient reported