Direct SARS-CoV-2 infection of the human inner ear may underlie COVID-19-associated audiovestibular dysfunction.
Minjin JeongKaren E OcwiejaDongjun HanPhillip Ashley WackymYichen ZhangAlyssa BrownCynthia MoncadaAndrea VambutasTheodore KanneRachel CrainNoah SiegelValerie LegerFelipe SantosD Bradley WellingLee GehrkeKonstantina M StankovicPublished in: Communications medicine (2021)
Our results provide mechanistic explanations of audiovestibular dysfunction in COVID-19 patients and introduce hiPSC-derived systems for studying infectious human otologic disease.