The Role of Tocilizumab in Glucocorticoid Resistant Giant Cell Arteritis: A Case Series and Literature Review.
Brandon StrettonYiran TanMark HassallSumu SimonPublished in: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society (2022)
We agree with existing hypothesis that tocilizumab likely prevents a "pending" central retinal artery occlusion by maintaining retinal vasculature perfusion. Our case series suggests that there is a role for tocilizumab as "rescue" therapy for GC-resistant GCA, where vision loss would otherwise be imminent.
Keyphrases
- rheumatoid arthritis
- giant cell
- juvenile idiopathic arthritis
- rheumatoid arthritis patients
- optical coherence tomography
- diabetic retinopathy
- disease activity
- optic nerve
- case report
- magnetic resonance imaging
- systemic lupus erythematosus
- computed tomography
- contrast enhanced
- mass spectrometry
- simultaneous determination