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Association of raltegravir use with long-term health outcomes in HIV-infected patients: an observational post-licensure safety study in a large integrated healthcare system.

Michael A HorbergAllison H OakesLeo B HurleyWilliam J TownerChun R ChaoMichael J SilverbergJean Q ChantraCourtney G EllisCharles P Quesenberry
Published in: HIV clinical trials (2018)
The potentially elevated risk for malignancy and mortality with raltegravir and residual confounding merits further investigation. We demonstrate the value of observational cohorts for monitoring post-licensure medication safety.
Keyphrases
  • hiv infected patients
  • antiretroviral therapy
  • healthcare
  • cross sectional
  • cardiovascular events
  • risk factors