GSK3β inhibition and canonical Wnt signaling in mice hearts after myocardial ischemic damage.

Lina BadimonLaura CasaníSandra Camino-LopezOriol Juan-BabotMaria Borrell-Pages

Published in: PloS one (2019)

These studies support a central role for GSK3β in the activation of the canonical Wnt pathway in the Wt heart. Although LRP5 is protective against myocardial injury, GSK3β expression levels do not regulate heart damage.

Keyphrases

pi k akt
signaling pathway
heart failure
oxidative stress
poor prognosis
cell proliferation
stem cells
atrial fibrillation
left ventricular
high fat diet induced
type diabetes
binding protein
adipose tissue
insulin resistance
brain injury