Multicenter validation of a machine learning phase space electro-mechanical pulse wave analysis to predict elevated left ventricular end diastolic pressure at the point-of-care.
Sanjeev P BhavnaniRola KhedrakiTravis J CohoonFrederick J MeineThomas D StuckeyThomas McMinnJeremiah P DeptaBrett BennettThomas McGarryWilliam CarrollDavid SuhJohn A SteuterMichael RobertsHorace R GillinsIan ShadforthEmmanuel LangeAbhinav DoomraMohammad FirouziFarhad FathiehTimothy BurtonAli KhosousiShyam RamchandaniWilliam E SandersFrank SmartPublished in: PloS one (2022)
The phase space ML analysis provides a robust prediction for an elevated LVEDP at the point-of-care. These data suggest a potential role for an OVG and PPG derived electro-mechanical pulse wave strategy to determine if LVEDP is elevated in patients with symptoms suggestive of cardiac disease.