Computational modeling of the immune response in multiple sclerosis using epimod framework.
Simone PerniceLaura FolliaAlessandro MaglioneMarzio PennisiFrancesco PappalardoFrancesco NovelliMarinella ClericoMarco BeccutiFrancesca CorderoSimona RollaPublished in: BMC bioinformatics (2020)
Simulation results have proven the ability of the model to reproduce in silico the immune T cell balance characterizing RRMS course and the DAC effects. Furthermore, they confirmed the importance of a timely intervention on the disease course.