The Distribution and Role of M1 and M2 Macrophages in Aneurysm Healing after Platinum Coil Embolization.

Zenith Khashim Daying Dai Yong-Hong Ding Jennifer Ayers-Ringler S Herting D Jakaitis Duncan J Maitland David F Kallmes Ramanathan D Kadirvel

Published in: AJNR. American journal of neuroradiology (2020)

Our data support the direct correlation between M2 macrophage polarization and healing in aneurysm tissues. Our results show a positive relationship between M2 macrophage populations and total histologic scores at later stages of healing after endovascular coiling. We conclude that interventions aimed at stimulating M2 macrophage expression locally may improve aneurysm healing after coil embolization.

Keyphrases

coronary artery
adipose tissue
poor prognosis
gene expression
abdominal aortic aneurysm
physical activity
big data
long non coding rna
internal carotid artery
deep learning