Identification of hub genes in bladder cancer based on weighted gene co-expression network analysis from TCGA database.

Lei WangXudong LiuMiao YueZhe LiuYu ZhangYing MaJia LuoWuling LiJiangshan BaiHongmei YaoYuxuan ChenXiaofeng LiDayun FengXinqiang Song

Published in: Cancer reports (Hoboken, N.J.) (2021)

The research suggests that CNKSR1, POPDC2, and PJA2 may be novel biomarkers as therapeutic targets for MIBC, especially we used immunohistochemical further to validate CNKSR1 as a therapeutic target for MIBC which may help to improve the prognosis for MIBC.

Keyphrases

network analysis
bioinformatics analysis
genome wide
genome wide identification
poor prognosis
copy number
genome wide analysis
dna methylation
emergency department
binding protein
long non coding rna
gene expression
magnetic resonance