Elevated circulating fasting glucagon-like peptide-1 in surgical patients with aortic valve disease and diabetes.
Camilla KrizhanovskiiStelia NtikaChristian OlssonPer ErikssonAnders Franco-CerecedaPublished in: Diabetology & metabolic syndrome (2017)
A subgroup of diabetic patients with aortic valve pathology have increased fasting plasma GLP-1 levels, which may be of importance for the low prevalence of aortic dilation in this patient group. Further, in TAV patients, GLP-1 secretion and plasma levels of intact GLP-1 are upregulated in association with aortic dilation, possibly indicating a compensatory mechanism.
Keyphrases
- aortic valve
- transcatheter aortic valve replacement
- transcatheter aortic valve implantation
- aortic valve replacement
- aortic stenosis
- type diabetes
- end stage renal disease
- ejection fraction
- blood glucose
- newly diagnosed
- insulin resistance
- chronic kidney disease
- cardiovascular disease
- peritoneal dialysis
- prognostic factors
- randomized controlled trial
- case report
- adipose tissue
- blood pressure
- coronary artery disease
- metabolic syndrome
- coronary artery
- patient reported
- atrial fibrillation
- pulmonary hypertension
- phase iii
- study protocol