A Retrospective Real-Life Multicenter Study on Concurrent Oral Preventive Treatments in Patients with Chronic Migraine Treated with OnabotulinumtoxinA.

Lucas Hendrik Overeem Raffaele Ornello Maria Magdalena Pocora Uwe Reuter Simona Sacco Cristina TassorelliAud Nome DuelandBianca Raffaelli Daniele Martinelli

Published in: CNS drugs (2023)

Prescription of oral concomitant preventive treatment is common in patients with chronic migraine receiving BoNTA. We did not identify any unexpected safety or tolerability issues in patients receiving BoNTA and a CT+M. However, patients with a CT+M experienced a smaller reduction in monthly headache days when compared with those with CT-, which might be associated with a higher resistance to treatment in that subgroup of patients.

Keyphrases

image quality
computed tomography
dual energy
contrast enhanced
ejection fraction
newly diagnosed
end stage renal disease
magnetic resonance imaging
randomized controlled trial
prognostic factors
open label
patient reported
study protocol