Guillain-Barré Syndrome with Incomplete Oculomotor Nerve Palsy after Traumatic Brain Injury: Case Report and Literature Review.
Jinsheng LiuFeng TangXinjun ChenZhi-Qiang LiPublished in: Brain sciences (2023)
Guillain-Barré syndrome (GBS) is a severe peripheral neuroinflammatory demyelinating disease characterized by symmetrical progressive limb weakness, which can be accompanied by cranial nerve and sensory disturbances. There is usually a history of bacterial or viral infection prior to onset. GBS is rarely seen after traumatic brain injury (TBI). We report a case of a 66-year-old male patient who presented with dilated pupils, followed by respiratory failure and symmetrical quadriplegia during a conservative treatment for TBI. He was eventually diagnosed with GBS and was treated with intravenous immunoglobulin, followed by rehabilitation therapy with a good recovery. We summarize previous similar cases and analyze possible causes. It is suggested that the possibility of GBS should be considered when unexplained symptoms occurred in patients with TBI, such as respiratory failure, dilated pupils, and limb weakness.
Keyphrases
- respiratory failure
- traumatic brain injury
- extracorporeal membrane oxygenation
- case report
- mechanical ventilation
- severe traumatic brain injury
- mild traumatic brain injury
- acute respiratory distress syndrome
- peripheral nerve
- multiple sclerosis
- intensive care unit
- early onset
- depressive symptoms
- stem cells
- newly diagnosed
- chemotherapy induced