Integrative metabolomic characterisation identifies altered portal vein serum metabolome contributing to human hepatocellular carcinoma.
Jinkai LiuWei GengHanyong SunChangan LiuFan HuangJie CaoLei XiaHongchuan ZhaoJianning ZhaiQing LiXiang ZhangMing KuangShunli ShenQiang XiaVincent Wai-Sun WongJun YuPublished in: Gut (2021)
The integrative metabolome analysis of serum, tissue and stool metabolites revealed unreported metabolic alterations in HCC patients. In portal vein, we identified elevated and depleted metabolites signifying that they might play a role in HCC development.