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MEsenchymal StEm cells for Multiple Sclerosis (MESEMS): a randomized, double blind, cross-over phase I/II clinical trial with autologous mesenchymal stem cells for the therapy of multiple sclerosis.

Antonio UccelliAlice LaroniLou BrundinMichel ClanetOscar FernandezSeyed Massood NabaviPaolo A MuraroRoberto S OliveriErnst W RadueJohann SellnerPer Soelberg SorensenMaria Pia SormaniJens Thomas WuerfelMario A BattagliaMark S Freedmannull null
Published in: Trials (2019)
Andalusia: NCT01745783 , registered on Dec 10, 2012. Badalona: NCT02035514 EudraCT, 2010-024081-21. Registered on 2012. Canada: ClinicalTrials.gov, NCT02239393 . Registered on September 12, 2014. Copenhagen: EudraCT, 2012-000518-13 . Registered on June 21, 2012. Italy: EudraCT, 2011-001295-19, and ClinicalTrials.gov, NCT01854957 . Retrospectively registered on May 16, 2013. London: Eudra CT 2012-002357-35, and ClinicalTrials.gov, NCT01606215 . Registered on May 25, 2012. Salzburg: EudraCT, 2015-000137-78 . Registered on September 15, 2015. Stockholm: ClinicalTrials.gov, NCT01730547 . Registered on November 21, 2012. Toulouse: ClinicalTrials.gov, NCT02403947 . Registered on March 31, 2015.
Keyphrases
  • multiple sclerosis
  • mesenchymal stem cells
  • clinical trial
  • double blind
  • bone marrow
  • computed tomography
  • randomized controlled trial
  • cell therapy
  • magnetic resonance
  • placebo controlled
  • open label
  • image quality
  • pet ct