Evaluation of the promoter methylation status of hypoxia factor 3A and interleukin-6 genes and expression levels of mir-130b and mir-146b in childhood obesity.

Esra Tekcan Nurten Kara Hasan Murat Aydın Ummet Abur Mohsen Abbaszadeh

Published in: Revista da Associacao Medica Brasileira (1992) (2022)

Results support that MicroRNA-130b and MicroRNA-146b are potential biomarkers for the prevention and early diagnosis of obesity. This is the first study on childhood obesity in the Middle Black Sea region of Turkey. We believe that the results obtained by expanding the studies in our country and neighboring countries will be more decisive.

Keyphrases

dna methylation
genome wide
poor prognosis
insulin resistance
metabolic syndrome
type diabetes
weight loss
gene expression
transcription factor
endothelial cells
weight gain
adipose tissue
body mass index
long non coding rna
case control