Association and Effectiveness of PAX1 Methylation and HPV Viral Load for the Detection of Cervical High-Grade Squamous Intraepithelial Lesion.
Mingzhu LiChao ZhaoYun ZhaoJingran LiXiaobo ZhangWei ZhangQingqing GaoLihui WeiPublished in: Pathogens (Basel, Switzerland) (2022)
had the highest specificity in diagnosing CIN2+, followed by HPV16/18 VL, which are higher than cytology ≥ASCUS. (4) Conclusions: Hypermethylation of PAX1 is associated with high HPV VL, especially HPV16/18, and both present advantageous specificity in detecting CIN2+.