Trismus, health-related quality of life, and trismus-related symptoms up to 5 years post-radiotherapy for head and neck cancer treated between 2007 and 2012.
Susan AghajanzadehCharlott KarlssonLisa TuomiMy EngströmCaterina FiniziaPublished in: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2023)
This study highlights that HNC patients suffering from radiotherapy-induced trismus report poorer HRQL and more trismus-specific symptoms compared to patients without trismus. These differences persist and increase up to at least 5 years following treatment completion. Hence, our results highlight that radiotherapy-induced trismus affects long-term HRQL, jaw symptoms, and pain, further stressing the need for early and structured intervention.
Keyphrases
- end stage renal disease
- newly diagnosed
- early stage
- ejection fraction
- chronic kidney disease
- randomized controlled trial
- chronic pain
- high glucose
- radiation induced
- peritoneal dialysis
- pain management
- depressive symptoms
- squamous cell carcinoma
- oxidative stress
- neuropathic pain
- physical activity
- patient reported outcomes
- endothelial cells
- drug induced
- combination therapy